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2004 Pformulate.
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Maltodextrin
1] Description:
White powder or granular white powder, available in a
variety of particle sizes and DE* values. Non-sweet, nutritive saccharide
polymers composed of D-glucose units linked primarily by alpha-1-4 bonds..*
DE = dextrose equivalents, a quantitative measure of the degree of starch
polymer hydrolysis. The higher the DE, the greater the extent of starch
hydrolysis. Can be used for sweetness
moderation. Maltodextrin with a DE of 5 is the least sweet, and is
approximately 1/10 as sweet as sucrose. Maltodextrin with a DE of 18 is
approximately 1/4 as sweet as sucrose.
2] Physical Characteristics:
|
Typical Properties |
DE
Value
|
Bulk
Density (g/cc)
|
Moisture
Content (%)
|
|
C*PharmŽ maltodextrins
|
7
|
0.45
|
<
4
|
|
C*PharmŽ maltodextrins
|
14
|
0.45
|
<
4
|
|
C*PharmŽ maltodextrins
|
18.5
|
0.45
|
<
4
|
|
MaltrinŽ
M040
|
5
|
0.51
|
<
6
|
|
MaltrinŽ
M050
|
5
|
0.54
|
<
6
|
|
MaltrinŽ
M100
|
10
|
0.54
|
<
6
|
|
MaltrinŽ
M150
|
15
|
0.57
|
<
6
|
|
MaltrinŽ
M180
|
18
|
0.61
|
<
6
|
|
MaltrinŽ
M440
|
5
|
0.30
|
<
6
|
|
MaltrinŽ
M500
|
10
|
0.34
|
<
6
|
|
MaltrinŽ
M510
|
10
|
0.56
|
<
6
|
|
MaltrinŽ
M550
|
15
|
0.35
|
<
6
|
|
MaltrinŽ
M580
|
18
|
0.40
|
<
6
|
|
MaltrinŽ
M700
|
10
|
0.13
|
<
6
|
3] Applications:
| Direct
compression |
All
purpose binder
and/or diluent, low hygroscopicity. Binding properties comparable to
polyvinylpyrrolidone.
C*PharmŽ maltodextrins
MaltrinŽ Grades M150 and M180, and
Maltrin QDŽ Grades M500, M510, M550, M580 |
|
|
| Wet
Granulation |
Binder
and diluent, low viscosity, cold water soluble
C*PharmŽ maltodextrins
MaltrinŽ Grades M040, M100, M150 |
|
|
| Aqueous
Film Coating |
Film
Former, cold water soluble, low viscosity, enhances color
MaltrinŽ Grades M040, M100, M180 |
|
|
| Encapsulation |
Free-flowing,
inert diluent; low hygroscopicity, cohesiveness
MaltrinŽ QD Grades M500, M510 |
|
|
| Liquids |
Easily
dispersible, cold water soluble, regulates sweetness, regulates viscosity,
inhibits crystal growth
MaltrinŽ Grades M100, M150, M200 |
|
|
| Creams
and Lotions |
Builds
solids, nonirritating filler, inhibits crystal growth, humectant
MaltrinŽ Grades M040, M100, M150 |
|
|
| Dry
Blending |
Low
hygroscopicity, inert carrier, selection of particle size and bulk density,
neutral flavor
C*PharmŽ maltodextrins
MaltrinŽ M100, and M700, and
MaltrinŽ
QD M500, M510 |
Note: Maltrin QD grades are agglomerated, low-density granules, dust-free and
free flowing
4] Suppliers:
Need a supplier?
Submit in Excipients Express!!!
5] References:
Direct Compression Brochure, Cerestar
MaltrinŽ Maltodextrins and Corn
Syrup Solids for Pharmaceuticals, 1998, Grain Processing Corporation
Pformulate/04/20/2000
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