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Gellan Gum

1] Description:  Exocellular heteropolysaccharide produced by fermentation.

2] Physical Characteristics:

High gel strength, high clarity, excellent film former, low use level, thermally reversible gel.

 

The gelling mechanism is cation induced. Ability to gel with any cation, including counterion of an active ingredient. By varying ion content and/or gel concentration, the gel texture can be easily modified.

 

Melting temperature can be modified to either be below or above 100° C depending on the types and concentrations of ions present.

 

Heat and pH stable (pH 3.5 – 10).

 

 

Kelcogelâ

Kelcogelâ F 

Particle Size

42 mesh

100 mesh

 

3] Applications:

 

Gelling agent

Liquid dosage forms

semi-solid dosage forms

Intact Gel Dosage Forms - Self-standing, self-lubricated, easy to swallow, oral dosage form

Disintegrant Tablets and capsules  
Adhesive Mucosal Delivery  
Transdermal delivery  
Film Coating  

Controlled Release Tablets

 

 

 

4] Suppliers:

CP Kelco Biopolymers Kelcogelâ , Kelcogelâ F, Kelcogel LT 100, FCC

 

Note: March/April supplement to the USP/NF Pharmacopoeial Forum contains the new gellan gum monograph.

 

Need a supplier? Submit in Excipients Express!!!

 

 

5] References:

Gellan Gum for Pharmaceutical Applications rev. 10/99, Kelco Biopolymers

Gellan Gum Gel (G3) A New Self-Lubricated, Easy to Swallow, Oral Dosage Form rev. 10/99, Kelco Biopolymers 

pformulate/01/25/2004